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Inventi Impact: Gene Medicines

Articles

  • Inventi:pgm/33497/20
    Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice
    Research 2021 : January - March
    Que T La, Binhai Ren, Grant J Logan, Sharon C Cunningham, Neeta Khandekar, Najah T Nassif, Bronwyn A Oâ??Brien, Ian E Alexander, Ann M Simpson

    Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR)\nto the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO),\nwith resultant reversal of diabetes, restoration of glucose tolerance and pancreatic transdifferentiation\n(PT), due to the expression of beta............................

    How to Cite this Article
    Attribution/ CC Compliant Citation: La, Que T., et al. \"Use of a Hybrid Adeno-Associated Viral Vector Transposon System\nto Deliver the Insulin Gene to Diabetic NOD Mice.\" Cells 9.10 (2020): 2227.\nhttps://doi:10.3390/cells9102227\nhttp://creativecommons.org/licenses/by/4.0/\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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